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Phenylhydrazine
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| Chemical Name | Phenylhydrazine |
| Synonyms | Hydrazinobenzene; Monophenylhydrazine; |
| CAS Number | 100-63-0 |
| Molecular Formula | C₆H₈N₂ |
| Appearance | Colourless to Yellow Oil |
| Molecular Weight | 108.14 |
| Storage | 4°C, Hygroscopic |
| Solubility | Chloroform, Methanol (Slightly) |
| Category | Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | An aryl hydrazine used in the preparation of various dyes and pharmaceutical compounds. It is used in the investigation of oligosaccharides as well as the structure of photosystem II. |
| Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package |
Phenylhydrazine: Properties, Uses, and Safety Concerns
Phenylhydrazine is an organic compound with the chemical formula C6H5NHNH2. It is a colorless to yellowish oily liquid with a faint aniline-like odor. Phenylhydrazine is commonly used as a reagent in organic chemistry, and it has several industrial applications. In this article, we will discuss the properties, uses, and safety concerns associated with phenylhydrazine.
Properties of Phenylhydrazine
Phenylhydrazine is a highly reactive and unstable compound that can explode when exposed to heat or flame. It has a boiling point of 242 °C and a melting point of -23 °C. It is slightly soluble in water but highly soluble in most organic solvents. Phenylhydrazine is a strong reducing agent and can react violently with oxidizing agents.
Uses of Phenylhydrazine
Phenylhydrazine has several industrial applications, including the following:
1. Pharmaceuticals
Phenylhydrazine is used as a starting material for the synthesis of various pharmaceuticals, such as isoniazid and phenylpropanolamine.
2. Pesticides
Phenylhydrazine is used as an intermediate in the synthesis of various pesticides, such as insecticides and herbicides.
3. Dyes
Phenylhydrazine is used in the production of various dyes, such as azo dyes and sulfur dyes.
4. Rubber Chemicals
Phenylhydrazine is used as an accelerator in the production of rubber chemicals.
5. Other Uses
Phenylhydrazine is also used in the production of explosives, photographic chemicals, and laboratory reagents.
Safety Concerns of Phenylhydrazine
Phenylhydrazine is a toxic and potentially carcinogenic compound that can cause serious health effects upon exposure. It is known to cause damage to the liver, kidneys, and blood cells. In addition, phenylhydrazine can be explosive and can react violently with oxidizing agents, acids, and bases.
Regulatory Measures for Phenylhydrazine
In the United States, the Occupational Safety and Health Administration (OSHA) has set a permissible exposure limit (PEL) of 1 ppm for phenylhydrazine in the workplace. The European Union has also established regulations for the use of phenylhydrazine in various industries.
Conclusion
Phenylhydrazine is a highly reactive and potentially dangerous chemical compound that has several industrial applications. It is important to handle this compound with care and take appropriate safety measures to prevent exposure and accidents.