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N,N-Dimethylformamide
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| Chemical Name | N,N-Dimethylformamide |
| Synonyms | DMF; DMF (amide); DMFA; Dimethylformamide; N,N-Dimethylformaldehyde; N,N-Dimethylmethanamide; N-Formyldimethylamine; NSC 5356; Virodene-P 058; N,N-Dimethyl-formamide |
| CAS Number | 68-12-2 |
| Molecular Formula | C₃H₇NO |
| Appearance | Colourless Liquid |
| Molecular Weight | 73.09 |
| Storage | 4°C, Inert atmosphere |
| Solubility | Chloroform (Soluble), Methanol (Slightly) |
| Category | Building Blocks; Miscellaneous; |
| Applications | N,N-Dimethylformamide can be used as analyte in analytical study and in physical, engineering or chemical process for preparation of dinuclear (phenyl)gold(I) biphenyl diisocyanide complex and its solvent-responsive photoluminescence with mech. reactivation. |
| Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package |
N,N-Dimethylformamide: The Solvent and its Uses
Introduction
N,N-Dimethylformamide, commonly abbreviated as DMF, is a versatile organic solvent that is widely used in various industries. It has a wide range of applications, including as a solvent for polymers, resins, and dyes, as well as in the production of pharmaceuticals, agrochemicals, and electronic components.
What is N,N-Dimethylformamide?
DMF is an organic compound with the chemical formula (CH3)2NC(O)H. It is a clear, colorless liquid that is miscible with water and many organic solvents. DMF has a high boiling point of 153 °C, which makes it an ideal solvent for high-temperature reactions.
Properties of DMF
- DMF has a high boiling point and low viscosity, making it an excellent solvent for dissolving high-molecular-weight polymers and resins.
- It has a low freezing point of -61 °C, which makes it useful in low-temperature reactions.
- DMF is a strong polar solvent, which means it has a high dielectric constant and is capable of dissolving ionic compounds.
- It has a relatively low toxicity compared to other solvents, but it is still classified as a hazardous material and requires careful handling.
Uses of DMF
In the Pharmaceutical Industry
DMF is widely used in the pharmaceutical industry as a solvent for drug production. It is used to dissolve active ingredients, aid in drug formulation, and improve drug delivery. DMF is also used as a reaction medium in the synthesis of new pharmaceutical compounds.
In the Polymer Industry
DMF is commonly used as a solvent in the polymer industry, where it is used to dissolve and process high-molecular-weight polymers and resins. It is also used in the production of fibers, films, and coatings.
In the Electronics Industry
DMF is used as a solvent in the electronics industry for the production of printed circuit boards, LCD displays, and other electronic components. It is also used as a cleaning agent for electronic parts and equipment.
In the Agrochemical Industry
DMF is used as a solvent and reaction medium in the production of agrochemicals, such as pesticides and herbicides.
Health and Safety Considerations
DMF is classified as a hazardous material and can pose health and safety risks if not handled properly. It can be harmful if inhaled, ingested, or absorbed through the skin. Exposure to high levels of DMF can cause liver damage, respiratory problems, and other health issues. It is important to follow proper safety procedures when handling DMF, including wearing protective clothing and using adequate ventilation.
Conclusion
DMF is a versatile solvent with a wide range of applications in various industries. Its unique properties make it an ideal solvent for high-temperature reactions, the dissolution of high-molecular-weight polymers and resins, and the production of pharmaceuticals, agrochemicals, and electronic components. However, its potential health and safety risks make it crucial to handle DMF with care and follow proper safety procedures.